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Cyclin D1 expression in gliomas

✍ Scribed by P. Cavalla; A. Dutto; R. Piva; P. Richiardi; R. Grosso; D. Schiffer


Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
212 KB
Volume
95
Category
Article
ISSN
0001-6322

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Cyclin-D1 over-expression represents one of several common alterations in the G 1 -S transition associated with malignancies. Conclusive evidences indicate that cyclin D1 is a proto-oncogene and the gene is amplified or rearranged in different tumour types. Since very little is known about aberratio