Cyclin D1 Amplification in Multiple Myeloma Is Associated With Multidrug Resistance Expression
β Scribed by Sewify, Eman M.; Afifi, Ola A.; Mosad, Eman; Zaki, Amen H.; El Gammal, Sahar A.
- Book ID
- 121496292
- Publisher
- Elsevier
- Year
- 2014
- Tongue
- English
- Weight
- 977 KB
- Volume
- 14
- Category
- Article
- ISSN
- 2152-2650
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
An important positive regulator of the cell cycle, cyclin D1, is often amplified and overexpressed in malignancies. Cyclin D1 aberrations were analysed in grade II-IV astrocytomas by fluorescence in situ hybridization (FISH), mRNA in situ hybridization and immunohistochemistry. Proliferation activit
## Abstract Cyclin D1 is a wellβknown cell cycle regulator. Recently, its proβsurvival function has been revealed in several tumors. Because increasing expression of cyclin D1 is a common event in oral squamous cell carcinoma (OSCC) and has been correlated with cisplatin resistance, we investigated