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Cyclical use of tamoxifen and high-dose medroxyprogesterone acetate in advanced estrogen receptor positive breast cancer

✍ Scribed by S. Gundersen; S. Kvinnsland; S. Lundgren; O. Klepp; E. Lund; O. Børmer; H. Høst

Publisher
Springer US
Year
1990
Tongue
English
Weight
440 KB
Volume
17
Category
Article
ISSN
0167-6806

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✍ Geoffrey Falkson; Hèndré C. Falkson 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 215 KB

Twenty-three evaluable patients with advanced breast cancer were treated with MPA, 1,400 mg/m2 daily PO for the first 6 months, and 500 mg/m2 daily PO thereafter. The median total dose was 191,400 mg in 88 days, with the maximum dose given to date 522,600 mg in 282 days. Most patients tolerated high