The pharmacokinetics of high-dose medroxyprogesterone acetate (MPA) in the therapy of advanced breast cancer
β Scribed by Hans Christian Blossey; Hans Helge Bartsch; Dietrich Kanne; Johannes Koebberling; Gerhard Arno Nagel
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 425 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
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Postmenopausal patients with metastatic breast cancer were treated with medroxyprogesterone acetate (MPA) (Clinovir) in dosages between 500 and 1500 mg orally per day. The relation of MPA plasma concentrations and endocrine effects were studied in a longitudinal fashion. MPA exerted suppressive effe
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