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CXCL4-platelet factor 4, heparin-induced thrombocytopenia and cancer

✍ Scribed by Per Morten Sandset

Book ID
117258504
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
202 KB
Volume
129
Category
Article
ISSN
0049-3848

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Simultaneous binding of heparin and plat
Simultaneous binding of heparin and platelet factor-4 to platelets: Further insights into the mechanism of heparin-induced thrombocytopenia
✍ Horne, McDonald K.; Hutchison, Karen J. πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 130 KB πŸ‘ 2 views

Heparin-induced thrombocytopenia (HIT) is mediated by antibody against complexes of platelet factor-4 (PF4) and heparin. Although it has been assumed that these complexes bind to platelets and provide a target for the antibody, this has never been demonstrated. Furthermore, there is evidence suggest