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Laboratory diagnosis of heparin-induced thrombocytopenia type II after clearance of platelet factor 4/heparin complex

✍ Scribed by J. Harenberg; L.C. Wang; U. Hoffmann; G. Huhle; M. Feuring


Book ID
114486434
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
86 KB
Volume
137
Category
Article
ISSN
1532-6543

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✍ Horne, McDonald K.; Hutchison, Karen J. πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 130 KB πŸ‘ 2 views

Heparin-induced thrombocytopenia (HIT) is mediated by antibody against complexes of platelet factor-4 (PF4) and heparin. Although it has been assumed that these complexes bind to platelets and provide a target for the antibody, this has never been demonstrated. Furthermore, there is evidence suggest