Simultaneous binding of heparin and plat
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Horne, McDonald K.; Hutchison, Karen J.
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Article
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1998
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John Wiley and Sons
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English
⚖ 130 KB
👁 2 views
Heparin-induced thrombocytopenia (HIT) is mediated by antibody against complexes of platelet factor-4 (PF4) and heparin. Although it has been assumed that these complexes bind to platelets and provide a target for the antibody, this has never been demonstrated. Furthermore, there is evidence suggest