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Heparin-induced thrombocytopenia: towards standardization of platelet factor 4/heparin antigen tests

✍ Scribed by A. GREINACHER; T. ITTERMANN; J. BAGEMÜHL; K. ALTHAUS; B. FÜRLL; S. SELLENG; N. LUBENOW; S. SCHELLONG; J. I. SHEPPARD; T.E. WARKENTIN


Book ID
109154431
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
211 KB
Volume
8
Category
Article
ISSN
1538-7933

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📜 SIMILAR VOLUMES


Simultaneous binding of heparin and plat
✍ Horne, McDonald K.; Hutchison, Karen J. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB 👁 2 views

Heparin-induced thrombocytopenia (HIT) is mediated by antibody against complexes of platelet factor-4 (PF4) and heparin. Although it has been assumed that these complexes bind to platelets and provide a target for the antibody, this has never been demonstrated. Furthermore, there is evidence suggest