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Current Protocols in Neuroscience || Pentylenetetrazol (PTZ) Kindling Model of Epilepsy

✍ Scribed by Crawley, Jacqueline N.; Gerfen, Charles R.; Rogawski, Michael A.; Sibley, David R.; Skolnick, Phil; Wray, Susan

Book ID
119938482
Publisher
John Wiley & Sons, Inc.
Year
2012
Weight
172 KB
Category
Article
ISBN-13
9780471142300

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Anticonvulsant effect of felbamate in the pentylenetetrazole kindling model of epilepsy in the rat
✍ O. Giorgi; G. Carboni; V. Frau; M. Orlandi; V. Valentini; A. Feldman; M. G. Cord πŸ“‚ Article πŸ“… 1996 πŸ› Springer-Verlag 🌐 English βš– 661 KB

The present study was designed to examine the ability of felbamate, a novel antiepileptic agent, to antagonize the increase in seizure severity (i.e., chemical kindling) produced by chronic treatment with initially subconvulsant doses of pentylenetetrazol (PTZ). Rats were treated with PTZ (30 mg/kg,