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Curcumin Induces High Levels of Topoisomerase I− and II−DNA Complexes in K562 Leukemia Cells

✍ Scribed by López-Lázaro, Miguel; Willmore, Elaine; Jobson, Andrew; Gilroy, Kathryn L.; Curtis, Hannah; Padget, Kay; Austin, Caroline A.

Book ID
120833058
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
209 KB
Volume
70
Category
Article
ISSN
0163-3864

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Selenite induces topoisomerase I and II-DNA complexes in K562 leukemia cells
✍ Miguel López-Lázaro; Elaine Willmore; Sarah L. Elliott; Caroline A. Austin 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 120 KB

## Abstract The essential trace element selenium is one of the most promising cancer chemopreventive agents. Data from preclinical studies have revealed that selenite, an inorganic form of selenium, may also be useful in cancer chemotherapy. DNA topoisomerases (topos) are the target of several usef