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Formation and longevity of idarubicin-induced DNA topoisomerase II cleavable complexes in K562 human leukaemia cells

โœ Scribed by Elaine Willmore; Fiona Errington; Michael J. Tilby; Caroline A. Austin


Book ID
113993042
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
339 KB
Volume
63
Category
Article
ISSN
0006-2952

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## Abstract The essential trace element selenium is one of the most promising cancer chemopreventive agents. Data from preclinical studies have revealed that selenite, an inorganic form of selenium, may also be useful in cancer chemotherapy. DNA topoisomerases (topos) are the target of several usef