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Culture of human dermal fibroblasts in collagen gels: Modulation of interleukin 1-induced prostaglandin E2 synthesis by an extracellular matrix

โœ Scribed by Robert M. Barr; Paul H. Symonds; Akunna S. Akpan; Malcolm W. Greaves


Book ID
115892719
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
853 KB
Volume
198
Category
Article
ISSN
0014-4827

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Platelet-derived growth factor (PDGF) is a biological mediator for connective tissue cells and plays a critical role in a wide variety of physiological and pathological processes. We here investigated the effect of PDGF on arachidonic acid release and prostaglandin E 2 (PGE 2 ) synthesis in human gi