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Synthesis and Inhibitory Effect of Novel Glycyrrhetinic Acid Derivatives on IL-1β-Induced Prostaglandin E2 Production in Normal Human Dermal Fibroblasts.

✍ Scribed by Michiko Tsukahara; Takeshi Nishino; Ikue Furuhashi; Hideo Inoue; Toshitsugu Sato; Hiroatsu Matsumoto


Publisher
John Wiley and Sons
Year
2006
Weight
16 KB
Volume
37
Category
Article
ISSN
0931-7597

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Platelet-derived growth factor (PDGF) is a biological mediator for connective tissue cells and plays a critical role in a wide variety of physiological and pathological processes. We here investigated the effect of PDGF on arachidonic acid release and prostaglandin E 2 (PGE 2 ) synthesis in human gi