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Crystallization and preliminary X-ray diffraction studies on a trypsin/chymotrypsin double-headed inhibitor from horse gram

โœ Scribed by Balaji Prakash; M.R.N. Murthy; Y.N. Sreerama; P.R. Rama Sarma; D. Rajagopal Rao


Book ID
117143890
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
212 KB
Volume
235
Category
Article
ISSN
0022-2836

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A toxic phospholipase A(2) (PLA(2)) is isolated from the neurotoxic complex Vipoxin, the major lethal component of the venom of Vipera ammodytes meridionalis. The enzyme is complexed to the synthetic inhibitor elaidoylamide and crystallized. The crystals belong to the space group P2(1)2(1)2(1), with