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Crystallization and Preliminary X-ray Analysis of Vipoxin, a Complex between a Toxic Phospholipase A2 and its Natural Polypeptide Inhibitor

✍ Scribed by Christian Betzel; Marcia Visanji; K.S. Wilson; Nicolay Genov; Ivanka Mancheva; Boris Aleksiev; Tej Singh

Book ID
115626024
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
160 KB
Volume
231
Category
Article
ISSN
0022-2836

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Crystallization and preliminary X-ray di
Crystallization and preliminary X-ray diffraction studies of a toxic phospholipase A2 from the venom of Vipera ammodytes meridionalis complexed to a synthetic inhibitor
✍ Dessislava Nikolova Georgieva; Wojciech Rypniewski; Markus Perbandt; Mahendra Ja πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 86 KB

A toxic phospholipase A(2) (PLA(2)) is isolated from the neurotoxic complex Vipoxin, the major lethal component of the venom of Vipera ammodytes meridionalis. The enzyme is complexed to the synthetic inhibitor elaidoylamide and crystallized. The crystals belong to the space group P2(1)2(1)2(1), with