Identification of a pharmacophore for nu
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Mark A. Fisher; Prem N. S. Yadav; Janardan Yadav; David Kristol; Edward Arnold;
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Article
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1994
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John Wiley and Sons
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English
β 493 KB
## Abstract An βactive analogβ approach to receptor mapping was used to identify a pharmacophore for a set of thymidine nucleoside analog inhibitors of HIVβ1 reverse transcriptase. The preliminary results indicate that the O2, O4β², and O5β² atoms are capable of adopting a unique pharmacophoric patte