✦ LIBER ✦

Crystal Structure of a Polyhistidine-Tagged Recombinant Catalytic Subunit of cAMP-Dependent Protein Kinase Complexed with the Peptide Inhibitor PKI(5−24) and Adenosine †

✍ Scribed by Narayana, Narendra; Cox, Sarah; Shaltiel, Shmuel; Taylor, Susan S.; Xuong, Nguyen-huu

Book ID: 127124806
Publisher: American Chemical Society
Year: 1997
Tongue: English
Weight: 290 KB
Volume: 36
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi961947+

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

2.2 Å refined crystal structure of the c

2.2 Å refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor

✍ Zheng, J. ;Trafny, E. A. ;Knighton, D. R. ;Xuong, N. ;Taylor, S. S. ;Ten Eyck, L 📂 Article 📅 1993 🏛 International Union of Crystallography 🌐 English ⚖ 966 KB

Solution structure of the cAMP-dependent

Solution structure of the cAMP-dependent protein kinase catalytic subunit and its contraction upon binding the protein kinase inhibitor peptide

✍ Olah, G. A.; Mitchell, R. D.; Sosnick, T. R.; Walsh, D. A.; Trewhella, J. 📂 Article 📅 1993 🏛 American Chemical Society 🌐 English ⚖ 1000 KB

Crystal Structure of the Potent Natural

Crystal Structure of the Potent Natural Product Inhibitor Balanol in Complex with the Catalytic Subunit of cAMP-Dependent Protein Kinase †

✍ Narayana, Narendra; Diller, Thomas C.; Koide, Kazunori; Bunnage, Mark E.; Nicola 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 169 KB

E230Q mutation of the catalytic subunit

E230Q mutation of the catalytic subunit of cAMP-dependent protein kinase affects local structure and the binding of peptide inhibitor

✍ Man-Un Ung; Benzhuo Lu; J. A. McCammon 📂 Article 📅 2006 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 484 KB 👁 2 views

## Abstract The active site of the mammalian cAMP‐dependent protein kinase catalytic subunit (C‐subunit) has a cluster of nonconserved acidic residues—Glu127, Glu170, Glu203, Glu230, and Asp241—that are crucial for substrate recognition and binding. Studies have shown that the Glu230 to Gln mutant

Crystal Structures of RIα Subunit of Cyc

Crystal Structures of RIα Subunit of Cyclic Adenosine 5‘-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with ( R p )-Adenosine 3‘,5‘-Cyclic Monophosphothioate and ( S p )-Adenosine 3‘,5‘-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP †,‡

✍ Wu, Jian; Jones, John M.; Xuong, Nguyen-Huu; Eyck, Lynn F. Ten; Taylor, Susan S. 📂 Article 📅 2004 🏛 American Chemical Society 🌐 English ⚖ 468 KB

Crystallization studies of cAMP-dependen

Crystallization studies of cAMP-dependent protein kinase: Cocrystals of the catalytic subunit with a 20 amino acid residue peptide inhibitor and MgATP diffract to 3.0 Å resolution

✍ Daniel R. Knighton; Nguyen Huu Xuong; Susan S. Taylor; Janusz M. Sowadski 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 465 KB