Since 1966 we treated 22 patients with ulcerative colitis, 15 of which with severe diseases were selected for immunosuppressive therapy according to strictly defined criteria. Difficulties were observed in 2 eases. In 13 cases immunosuppressive therapy promptly resulted in clinical and reetoseopic r
Cryptococcus neoformans infection in ulcerative colitis with immunosuppressants
β Scribed by Li-Ping Chen; Jin Li; Mei-Fang Huang; Qing-Song Chen; Bing Xia
- Book ID
- 102268183
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 108 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1078-0998
No coin nor oath required. For personal study only.
β¦ Synopsis
To the Editor:
The etiology of ulcerative colitis (UC) remains unclear. As effective drugs for induction of remission and maintenance therapy for the disease, immunomodulators are often used in UC patients. Cryptococcus neoformans infection in UC patients using immunomodulators occurs rarely; herein we reported two cases and reviewed the relevant literature.
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A close correlation was observed between body weight and length of the survival time of mice inoculated intravenously (i.v.)with Cryptococeus neoformans (p < 0.001). An endotoxic substance of C. neoformans (Cr-ET) increased the susceptibility of mice to i.v. infection of C. neoformans only when more