To the Editor: The etiology of ulcerative colitis (UC) remains unclear. As effective drugs for induction of remission and maintenance therapy for the disease, immunomodulators are often used in UC patients. Cryptococcus neoformans infection in UC patients using immunomodulators occurs rarely; herei
Experiences with immunosuppressive therapy in childhood ulcerative colitis
✍ Scribed by Sch�fer, K. -H. ;Bl�ker, F.
- Book ID
- 104774545
- Publisher
- Springer-Verlag
- Year
- 1971
- Weight
- 556 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0044-2917
No coin nor oath required. For personal study only.
✦ Synopsis
Since 1966 we treated 22 patients with ulcerative colitis, 15 of which with severe diseases were selected for immunosuppressive therapy according to strictly defined criteria. Difficulties were observed in 2 eases. In 13 cases immunosuppressive therapy promptly resulted in clinical and reetoseopic remissions. Roentgenologic findings of colon were normalized in 2 cases, improved in 3 cases and not yet controlled in the other eases. Side effects were noted in 2 patients, they included cholestatic jaundice and vomiting. Alopeeia and decreased linear growth were not observed.
In summary our experience with the immunosuppressive therapy of childhood ulcerative colitis so far has been encouraging.
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