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Cryptic 5′ MLL gene insertion in an X-chromosome in acute myeloblastic leukemia

✍ Scribed by Nathalie Douet-Guilbert; Bertrand Arnaud; Frédéric Morel; Marie-Josée Le Bris; Marc De Braekeleer


Book ID
113512559
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
200 KB
Volume
157
Category
Article
ISSN
0165-4608

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## Abstract The formation of a leukemogenic fusion product in hematopoietic malignancies is commonly achieved by chromosomal translocation. Alternate and cytogenetically undetectable mechanisms of fusion transcript generation have been documented for __BCR__–__AB1__, __AML1__–__ETO__, __PML__–__RAR