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Critical residue combinations dictate peptide presentation by MHC class II molecules

✍ Scribed by Jean-François Hernandez; François Cretin; Suzanne Lombard-Platet; Jean-Paul Salvi; Nadia Walchshofer; Denis Gerlier; Joelle Paris; Chantal Rabourdin-Combe

Book ID: 119142947
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 915 KB
Volume: 15
Category: Article
ISSN: 0196-9781
DOI: 10.1016/0196-9781(94)90080-9

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Particularly prominent during the past year was the analysis of the subcellular compartment in which MHC class II molecules are located. Some investigators also analyzed the site where peptides are generated for MHC class II binding. Studies of invariant chain were particularly important in trying t