𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Crippling p53 activities via knock-in mutations in mouse models

✍ Scribed by Iwakuma, T; Lozano, G


Book ID
110072275
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
254 KB
Volume
26
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Regulation of P53 stability in p53 mutat
✍ Stephan Hailfinger; Maike Jaworski; Philip Marx-Stoelting; Ines Wanke; Michael S πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 French βš– 657 KB

## Abstract The tumor suppressor p53 is frequently mutated in cancer. We have investigated the regulation of P53 in p53 wild type mouse hepatoma cells (line 55.1c), in p53 heterozygeously mutated cells (56.1b) and in p53 defective cells (lines 56.1d, 70.4 and HUH7) under various experimental settin

Identification of RB and p53 mutations i
✍ Akira Murakami; Harutaka Tanaka πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 339 KB

We analyzed the genomic structure and mRNA of the RB and p53 genes in four mouse lymphoid leukemia cell lines (DL-1, DL-5, DL-8, and DL-12). Although no gross structural alteration of the RB gene was observed in any cell line, abnormalities of RB mRNA were detected in at least two cell lines. RB mRN

Aflatoxin-B exposure does not lead to p5
✍ Wei-Min Tong; Ming-Kei Lee; Dominique Galendo; Zhao-Qi Wang; Kanaga Sabapathy πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 French βš– 366 KB

## Abstract Hepatocellular carcinoma (HCC) is a common human malignancy that is often associated with risk factors such as aflatoxin‐B~1~ (AFB~1~) exposure and Hepatitis‐B virus infection in developing countries. There is a strong correlation between these risk factors and mutation of the tumor‐sup