cRGD-Functionalized Polymer Micelles for Targeted Doxorubicin Delivery
โ Scribed by Norased Nasongkla; Xintao Shuai; Hua Ai; Brent D. Weinberg; John Pink; David A. Boothman; Jinming Gao
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 255 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Cationic polymers have been chemically modified with a variety of targeting molecules such as peptides, proteins, antibodies, sugars and vitamins for targeted delivery of nucleic acid drugs to specific cells. Stimuliโsensitive polymers exhibiting different size, charge and conformation
## Abstract To overcome multidrug resistance (MDR) existing in tumor chemotherapy, polymeric micelles encoded with folic acid on the micelle surface were prepared with the encapsulation of a potent MDR modulator, FG020326. The micelles were fabricated from diblock copolymers of poly(ethylene glycol
## Abstract PLGAโgrafted HA copolymers were synthesized and utilized as target specific micelle carriers for DOX. For grafting hydrophobic PLGA chains onto the backbone of hydrophilic HA, HA was solubilized in an anhydrous DMSO by nanoโcomplexing with dimethoxyโPEG. The carboxylic groups of HA were
## Abstract Amphiphilic biodegradable succinylchitosan nanoparticles modified with folic acid are described that act as an emulsifier to form nanoparticles. Their molecular structures and physicochemical as well as selfโassembly properties are characterized by means of FTโIR, ^1^H NMR, FESEM, DLS,
In this study, the cytotoxicity of doxorubicin (DOX) loaded stearic acid grafted chitosan oligosaccharide (CSO-SA) micelles and its core modified drug delivery systems were investigated in vitro. The in vitro drug release experiments using cellular culture medium, Roswell Park Memorial Institute 164