✦ LIBER ✦

Cover Picture: Eur. J. Immunol. 1/12

✍ Scribed by Paul Rouzaire; Carmelo Luci; Elisabeth Blasco; Jacques Bienvenu; Thierry Walzer; Jean-François Nicolas; Ana Hennino

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 363 KB
Volume: 42
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.201190084

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The cover shows a histological analysis of an ear section from a C57BL/6 mouse that was first sensitised with 2,4‐dinitrofluorobenzene on the belly and then challenged 4 days later with 2,4‐dinitrofluorobenzene on the ear. Haematoxylin and eosin staining shows massive skin infiltration by mononuclear cells and granulocytes 24 h after challenge. The image is from Rouzaire et al. (pp. 80–88) in which the authors show that NK cells and T cells induce different types of inflammatory reactions in the skin during recall responses to haptens; of note, NK cell‐mediated pathogenesis does not rely on cellular infiltrate.

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