Coupling of Open Tubular Liquid Chromatography to Electrospray Mass Spectrometry with a Nanospray Interface
β Scribed by Hulthe, Gustaf; Petersson, Maria A.; Fogelqvist, Elisabet
- Book ID
- 126903589
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 136 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0003-2700
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π SIMILAR VOLUMES
When packed capillary columns are coupled to electrospray mass spectrometry, care must be taken to reduce the dead volumes of the detector connections. In this work, the coupling between the column and the detector was made with a 20-m i.d. fused silica capillary which was inserted in the electrospr
## Abstract A novel interface that allows normalβphase liquid chromatography to be coupled with electrospray ionization (ESI) is reported. A makeβup solution of 60 mM ammonium acetate in methanol, infused at a 5 Β΅l min^β1^ flowβrate at the tip of the electrospray probe, provides a sheath liquid whi