Characterization of the direct-probe open-tubular liquid chromatography-mass spectrometry interface parameters
β Scribed by Jos S.M. De Wit; Kenneth B. Tomer; James W. Jorgenson
- Book ID
- 108335374
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 679 KB
- Volume
- 462
- Category
- Article
- ISSN
- 1873-3778
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## Abstract Mass spectra of solutes can be obtained by direct introduction of the solution into a chemical ionization source. This should facilitate direct monitoring of the effluent from liquid chromatography columns with nanogram sensitivity.
## Abstract We have applied an electrophoresisβassisted openβtubular LCβMS method for analyzing intact lipopolysaccharides (LPSs) from __Haemophilus influenzae__ strain RM118 (Rd). We were able to obtain structural information on both core oligosaccharides (OSs) and the lipid A moiety including the