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Coumarin induced acral skin necrosis associated with hereditary protein C deficiency

✍ Scribed by Pabinger, I. ;Karnik, R. ;Lechner, K. ;Slany, J. ;Niessner, H.

Publisher
Springer-Verlag
Year
1986
Weight
351 KB
Volume
52
Category
Article
ISSN
1432-0584

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Skin necrosis is a rare but debilitating complication of treatment with vitamin K antagonist anticoagulants such as warfarin. A clinically similar syndrome has been reported less frequently with heparin therapy. We recently managed a thirty-year-old female patient who developed skin necrosis on her