Skin necrosis following prolonged administration of coumarin in a patient with inherited protein S deficiency

Anticoagulant-induced skin necrosis in a

Anticoagulant-induced skin necrosis in a patient with hereditary deficiency of protein S

✍ Gailani, David; Reese, Eugene P. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 74 KB 👁 2 views

Skin necrosis is a rare but debilitating complication of treatment with vitamin K antagonist anticoagulants such as warfarin. A clinically similar syndrome has been reported less frequently with heparin therapy. We recently managed a thirty-year-old female patient who developed skin necrosis on her