Cost-effectiveness analysis of lamivudine and adefovir dipivoxil in the treatment of patients with HBeAg-negative chronic hepatitis B
✍ Scribed by M. BUTI; M. A. CASADO; J. L. CALLEJA; J. SALMERÓN; J. AGUILAR; M. RUEDA; R. ESTEBAN
- Book ID
- 108604415
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 151 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0269-2813
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Although adefovir dipivoxil (ADV) has a unique profile of delayed and infrequent resistance in treatment-naïve chronic hepatitis B patients, the association of ADV resistance with previous lamivudine (LAM) resistance is not well understood. We compared the emergence of the ADV-resistant mutations rt
## Abstract Factors influencing the therapeutic efficacy of adefovir dipivoxil added to continuing lamivudine have not been elucidated in lamivudine‐resistant patients with type B chronic hepatitis. The viral mutations influencing the efficacy of treatment with adefovir dipivoxil were investigated