Factors contributing to antiviral effect of adefovir dipivoxil therapy added to ongoing lamivudine treatment in patients with lamivudine-resistant chronic hepatitis B
✍ Scribed by Nao Kurashige; Naoki Hiramatsu; Kazuyoshi Ohkawa; Takayuki Yakushijin; Shinichi Kiso; Tatsuya Kanto; Tetsuo Takehara; Akinori Kasahara; Yoshinori Doi; Akira Yamada; Masahide Oshita; Eiji Mita; Hideki Hagiwara; Toshihiko Nagase; Harumasa Yoshihara; Eijiro Hayashi; Yasuharu Imai; Michio Kato; Takeshi Kashihara; Norio Hayashi
- Book ID
- 106180465
- Publisher
- Springer Japan
- Year
- 2009
- Tongue
- English
- Weight
- 321 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0944-1174
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Factors influencing the therapeutic efficacy of adefovir dipivoxil added to continuing lamivudine have not been elucidated in lamivudine‐resistant patients with type B chronic hepatitis. The viral mutations influencing the efficacy of treatment with adefovir dipivoxil were investigated
## Abstract The aims of this study were to assess the long‐term efficacy of lamivudine (LAM) plus adefovir dipivoxil (ADV) combination therapy in patients with chronic hepatitis B resistant to LAM, to identify predictive factors of complete viral response (HBV‐DNA <2.6 log copies/ml at 12 months of
Entecavir (ETV) is currently recommended as a rescue therapy purely for adefovir (ADV)resistant chronic hepatitis B virus (HBV) infections. We evaluated the efficacy of ETV in patients who were resistant to lamivudine (LAM)/ADV sequential therapy and in those resistant to LAM monotherapy. Fifty LAM/
## Abstract Adefovir has a potent antiviral activity as a rescue treatment against lamivudine‐resistant strains. The aim of this study was to assess the patterns of lamivudine‐resistant mutations and their influence on the virologic response to adefovir rescue therapy in patients with lamivudine‐re