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Corticotropin-Releasing Factor-Induced Stimulation of Immune Functions

✍ Scribed by VIJENDRA K. SINGH; R. P. WARREN; E. D. WHITE; S. J. CHRISTINE LEU


Book ID
119865083
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
175 KB
Volume
594
Category
Article
ISSN
0890-6564

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The mitogenic effect of corticotropin-releasing factor (CRF) on rat lymphocytes was investigated. When rat splenocytes were cultured for 48 hr with CFR, a dosedependent increase in incorporation of 3H-thymidine (3H-Tdr) was observed, with a maximal response at 10 nM CRF. Comparison of the proliferat