The mitogenic effect of corticotropin-releasing factor (CRF) on rat lymphocytes was investigated. When rat splenocytes were cultured for 48 hr with CFR, a dosedependent increase in incorporation of 3H-thymidine (3H-Tdr) was observed, with a maximal response at 10 nM CRF. Comparison of the proliferat
โฆ LIBER โฆ
Functional stimulation of natural killer cells by corticotropin-releasing factor
โ Scribed by Vijendra K. Singh; Sy-Jye Christine Leu
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 92 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0192-0561
No coin nor oath required. For personal study only.
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## Abstract The __in vitro__ cytotoxicity of rat natural killer cells was augmented by the incubation of normal spleen cells with a soluble factor derived from the 24โh culture of spleen cells and various tumour cells. Cytotoxicity was augmented approximately 4โ, 3โ or 2โfold depending on whether t
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