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Correlation of the occurrence of YMDD mutations with HBV genotypes, HBV-DNA levels, and HBeAg status in Chinese patients with chronic hepatitis B during lamivudine treatment

✍ Scribed by Feng Wu; Min-Jin Wu; Xiao-Lin Zhuge; Shao-Ming Zhu; Biao Zhu

Book ID: 117792729
Publisher: Zhejiang University School of Medicine, China
Year: 2012
Tongue: English
Weight: 111 KB
Volume: 11
Category: Article
ISSN: 1499-3872
DOI: 10.1016/s1499-3872(12)60144-1

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## Abstract Peginterferon (PEG‐IFN) results in HBeAg loss combined with virologic response in only a minority of patients with HBeAg positive chronic hepatitis B. Baseline predictors of response to PEG‐IFN include HBV‐genotype, pre‐treatment HBV DNA levels, and ALT. The aims of this study were to d