Prediction of response to entecavir therapy in patients with HBeAg-positive chronic hepatitis B based on on-treatment HBsAg, HBeAg and HBV DNA levels
β Scribed by J. W. Shin; S. W. Jung; B. R. Park; C. J. Kim; J. B. Eum; B. G. Kim; I. D. Jeong; S.-J. Bang; S.-H. Lee; S. R. Kim; N. H. Park
- Book ID
- 117947772
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 98 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1352-0504
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Ferenci is a consultant for, advises, is on the speakers' bureau of, and received grants from Roche. Dr. Janssen is a consultant for and received grants from Roche, Bristol-Myers Squibb, Schering-Plough, Novartis, and Gilead. Dr. Flisiak received grants from Roche.
## Abstract Peginterferon (PEGβIFN) results in HBeAg loss combined with virologic response in only a minority of patients with HBeAg positive chronic hepatitis B. Baseline predictors of response to PEGβIFN include HBVβgenotype, preβtreatment HBV DNA levels, and ALT. The aims of this study were to d