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Correlation of psychotomimetic activity of phenethylamines and amphetamines with 1-octanol-water partition coefficients

โœ Scribed by Barfknecht, C. F.; Nichols, David E.; Dunn, W. J.

Book ID
126223206
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
354 KB
Volume
18
Category
Article
ISSN
0022-2623

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๐Ÿ“œ SIMILAR VOLUMES

Correlation of water solubility with oct
Correlation of water solubility with octanol-water partition coefficient: A response
โœ Samuel H. Yalkowsky; Shri C. Valvani ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 233 KB

Water (2.3 M ) dissolved in octanol( 6) reduces solute solubility in octanol, while octanol(4.5 X lO-3M) in water (9) enhances solute solubility in water. To support this point, the solubilities of these three compounds in water-saturated octanol are shown to be reduced by -10-30% because of water s