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Water solubility and octanol/water partition coefficients of organics. Limitations of the solubility-partition coefficient correlation

✍ Scribed by Banerjee, Sujit.; Yalkowsky, Samuel H.; Valvani, C.

Book ID
120429349
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
348 KB
Volume
14
Category
Article
ISSN
0013-936X

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πŸ“œ SIMILAR VOLUMES

Correlation of water solubility with oct
Correlation of water solubility with octanol-water partition coefficient: A response
✍ Samuel H. Yalkowsky; Shri C. Valvani πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 233 KB

Water (2.3 M ) dissolved in octanol( 6) reduces solute solubility in octanol, while octanol(4.5 X lO-3M) in water (9) enhances solute solubility in water. To support this point, the solubilities of these three compounds in water-saturated octanol are shown to be reduced by -10-30% because of water s