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Correlation of CpG island methylator phenotype with poor prognosis in hepatocellular carcinoma

✍ Scribed by Yue Cheng; Changsong Zhang; Jun Zhao; Chenyang Wang; Yun Xu; Zhipeng Han; Guocheng Jiang; Xianling Guo; Rong Li; Xinxin Bu; Mengchao Wu; Lixin Wei

Book ID
113956665
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
614 KB
Volume
88
Category
Article
ISSN
0014-4800

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## Abstract CpG island methylator phenotype (CIMP) involves the targeting of multiple genes by promoter hypermethylation. Telomerase plays an important role in the development of cellular immortality and oncogenesis. To gain insight into the role of epigenetic aberration of telomerase‐related genes