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CpG Island Methylator Phenotype Associated with Tumor Recurrence in Tumor–Node–Metastasis Stage I Hepatocellular Carcinoma

✍ Scribed by Binkui Li; Wenji Liu; Li Wang; Meixiang Li; Jianping Wang; Liang Huang; Pinzhu Huang; Yunfei Yuan


Book ID
111773449
Publisher
Springer
Year
2010
Tongue
English
Weight
335 KB
Volume
17
Category
Article
ISSN
1068-9265

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## Abstract CpG island methylator phenotype (CIMP) involves the targeting of multiple genes by promoter hypermethylation. Telomerase plays an important role in the development of cellular immortality and oncogenesis. To gain insight into the role of epigenetic aberration of telomerase‐related genes