Correlation of appearance of metastasis-associated protein1 (Mta1) with spermatogenesis in developing mouse testis
β Scribed by Wei Li; Jinshan Zhang; Xinping Liu; Ruojun Xu; Yuanqiang Zhang
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 799 KB
- Volume
- 329
- Category
- Article
- ISSN
- 0302-766X
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The mta1 gene is a recently identified novel candidate metastasis-associated gene. The deduced amino acid sequence contains an src homology-3 domain binding motif, a zinc finger motif and possible phosphorylation sites, suggesting that this gene is involved in signal transduction or regulation of ge
## Abstract Metastasisβassociated protein MTA1 and histone deacetylase form a protein complex with histone deacetylase activity that plays an important role in histone deacetylation, alteration of chromatin structure and transcriptional control. The precise role of the MTA1 protein in the malignant