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Association of latent membrane protein 1 and matrix metalloproteinase 9 with metastasis in nasopharyngeal carcinoma

✍ Scribed by Toshiyuki Horikawa; Tomokazu Yoshizaki; Tzung-Shiahn Sheen; Shiann-Yann Lee; Mitsuru Furukawa


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
801 KB
Volume
89
Category
Article
ISSN
0008-543X

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## Abstract Latent membrane protein 1 (LMP‐1) is an Epstein‐Barr virus‐encoded oncoprotein expressed in ∼50–70% of nasopharyngeal carcinoma (NPC). Previous studies have shown that NPC‐derived LMP‐1 variants carrying 30 bp deletion and specific mutations in the 3β€²C‐terminal region confer high oncoge