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Correlation between the inhibition of cell growth by bis(ethyl)polyamine analogues and the decrease in the function of mitochondria

โœ Scribed by Yong HE; Toshikazu SUZUKI; Keiko KASHIWAGI; Kuniko KUSAMA-EGUCHI; Akira SHIRAHATA; Kazuei IGARASHI

Book ID
115130750
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
850 KB
Volume
221
Category
Article
ISSN
1432-1327

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Inhibition of cell growth in CaCO2 cells
Inhibition of cell growth in CaCO2 cells by the polyamine analogue N1,N12-bis(ethyl)spermine is preceded by a reduction in MYC oncoprotein levels
โœ Craig M. Berchtold; Pamela Tamez; Thomas W. Kensler; Robert A. Casero Jr. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 195 KB ๐Ÿ‘ 1 views

The polyamine analogue N 1 ,N 12 bis(ethyl)spermine (BESpm) is a potent inhibitor of cell proliferation and is representative of a class of agents currently in clinical trials. Previous studies have demonstrated that BESpm treatment can produce a decrease in the mRNA levels of the protooncogene c-my