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Differential induction of spermidine/spermine N1-acetyltransferase in human lung cancer cells by the bis(ethyl)polyamine analogues


Book ID
123442474
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
156 KB
Volume
6
Category
Article
ISSN
0169-5002

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Regulation of spermidine/spermine N1-ace
โœ M. Alfonsina Desiderio; Giovanna Pogliaghi; Paola Dansi ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 291 KB ๐Ÿ‘ 2 views

Spermidine/spermine N 1 -acetyltransferase (cSAT), a key enzyme in polyamine degradation, is induced by various hepatotoxins and liver tumor promoters. In this paper we demonstrate that physiological factors, such as cytokines, control cSAT expression in HepG2 human hepatocarcinoma cells. Hepatocyte