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Correlation between chromosomal abnormalities and blast phenotype in the blast crisis of Ph-positive CGL

✍ Scribed by L. Parreira; L. Kearney; F. Rassool; V.B. Babapulle; E. Matutes; A. Parreira; J. Tavares de Castro; J.M. Goldman; D. Catovsky


Book ID
119103255
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
335 KB
Volume
22
Category
Article
ISSN
0165-4608

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A 23-year-old man developed Ph'-positive chronic myelogenous leukemia in 1966. After two short courses of busulfan not associated with severe myelosuppression, the frequency of Ph'-positive metaphases in his bone marrow was 40%. Over the next eight years, he remained hematologically stable without f