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Correlation of M-bcr breakpoint with different chromosomal abnormalities in blast crisis Ph1-positive CML

✍ Scribed by Ken I. Mills; Janet Stewart; Alan K. Burnett


Book ID
113239346
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
393 KB
Volume
15
Category
Article
ISSN
0145-2126

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Cytogenetic analysis is the gold standard for the follow-up of CML patients. The sensitivity of cytogenetics is fairly similar to that of Southern detection of M-BCR rearrangement (5%); this last technique has the potential advantage of being independent of cell division and yield of metaphases. IFN