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Corrections - Inhibitors of the Isoprenylated Protein Endoprotease

โœ Scribed by Ma, Yu-Ting; Gilbert, Bryant; Rando, Robert

Book ID
126144599
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
28 KB
Volume
32
Category
Article
ISSN
0006-2960

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๐Ÿ“œ SIMILAR VOLUMES

Inhibitors of Protein:Farnesyl Transfera
Inhibitors of Protein:Farnesyl Transferase and Protein:Geranylgeranyl Transferase I: Synthesis of Homologous Diphosphonate Analogs of Isoprenylated Pyrophosphate
โœ Mark Overhand; Hanneke R. Stuivenberg; Elsbet Pieterman; Louis H. Cohen; Rick E. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 297 KB

Novel diphosphonate homologs 7a-7c, and their cyclic counterparts 8a-8c, of the previously synthesized farnesyl pyrophosphate analogs 1 and 2 were prepared and tested for their inhibition potency and specificity of the enzymes PFT and PGGT-I. Compound 2 was shown to be the most potent inhibitor of P