Copper(i)-catalyzed synthesis of 1,3-enynes via coupling between vinyl halides and alkynes or domino coupling of vinyl halides
โ Scribed by Zhu, Yan; Li, Tingyi; Qu, Xiaoming; Sun, Peng; Yang, Hailong; Mao, Jincheng
- Book ID
- 115499871
- Publisher
- Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 251 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1477-0520
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๐ SIMILAR VOLUMES
Coupling reaction of aryl and vinyl halides with terminal alkynes using a catalyst system of copper(I) iodide -triphenylphosphine proceeds efficiently in the presence of potassium carbonate to give the corresponding unsymmetrical acetylenes in good yield.
Vinylic halides or triflates react with 3-butenoic or 4-pentenoic acids in the presence of 5% Pd(OAc) or Pd(dba) dimethylformamide at 8 -100ยฐC 6
Palladium/copper (I) halide catalyzed cross couplings of (E)-and (Z)-I,2difluorovinyistannanes with aryl iodides and vinyl halides proceeded at room temperature to stereospecifically give 1,2-disubstituted-l,2-difluoroolef'ms and 1,2difluoro or 1,2,3,4-tetrafluorosubstituted dienes in good to excell