𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Copper-Mediated Coupling of 1,1-Dibromo-1-alkenes with Nitrogen Nucleophiles: A General Method for the Synthesis of Ynamides

✍ Scribed by Alexis Coste; Ganesan Karthikeyan; François Couty; Gwilherm Evano

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
406 KB
Volume
48
Category
Article
ISSN
0044-8249

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Mild reaction conditions are the advantage of the title reaction, which allows straightforward entry to a variety of ynamides starting from readily available 1,1‐dibromo‐1‐alkenes, which act as attractive alkynylating agents (see scheme; EWG=electron‐withdrawing group, DMF=N,N‐dimethylformamide).magnified image

📜 SIMILAR VOLUMES

ChemInform Abstract: Copper-Mediated Cou
ChemInform Abstract: Copper-Mediated Coupling of 1,1-Dibromo-1-alkenes with Nitrogen Nucleophiles: A General Method for the Synthesis of Ynamides.
✍ Alexis Coste; Ganesan Karthikeyan; Francois Couty; Gwilherm Evano 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 35 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: Copper-Mediated Cro
ChemInform Abstract: Copper-Mediated Cross-Coupling of 1,1-Dibromo-1-alkenes with Dialkyl Phosphites: A Convenient Synthesis of 1-Alkenylphosphonates.
✍ Gwilherm Evano; Krishnaji Tadiparthi; Francois Couty 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 53 KB 👁 1 views

## Abstract The Hirao reduction of 1,1‐dibromo‐1‐alkenes with diisopropyl phosphite generates intermediate 1‐alkenylbromides, which react with a second equivalent phosphite to afford desired 1‐alkenylphoshonates.