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ChemInform Abstract: Copper-Mediated Cross-Coupling of 1,1-Dibromo-1-alkenes with Dialkyl Phosphites: A Convenient Synthesis of 1-Alkenylphosphonates.

✍ Scribed by Gwilherm Evano; Krishnaji Tadiparthi; Francois Couty

Publisher
John Wiley and Sons
Year
2011
Weight
53 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

The Hirao reduction of 1,1‐dibromo‐1‐alkenes with diisopropyl phosphite generates intermediate 1‐alkenylbromides, which react with a second equivalent phosphite to afford desired 1‐alkenylphoshonates.

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ChemInform Abstract: Copper-Mediated Cou
ChemInform Abstract: Copper-Mediated Coupling of 1,1-Dibromo-1-alkenes with Nitrogen Nucleophiles: A General Method for the Synthesis of Ynamides.
✍ Alexis Coste; Ganesan Karthikeyan; Francois Couty; Gwilherm Evano 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Copper-Mediated Coupling of 1,1-Dibromo-
Copper-Mediated Coupling of 1,1-Dibromo-1-alkenes with Nitrogen Nucleophiles: A General Method for the Synthesis of Ynamides
✍ Alexis Coste; Ganesan Karthikeyan; François Couty; Gwilherm Evano 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 406 KB 👁 2 views

## Abstract Mild reaction conditions are the advantage of the title reaction, which allows straightforward entry to a variety of ynamides starting from readily available 1,1‐dibromo‐1‐alkenes, which act as attractive alkynylating agents (see scheme; EWG=electron‐withdrawing group, DMF=__N__,__N__‐d