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Copper-Catalyzed Regioselective Intramolecular Oxidative α-Functionalization of Tertiary Amines: An Efficient Synthesis of Dihydro-1,3-Oxazines

✍ Scribed by Deb, Mohit L.; Dey, Suvendu S.; Bento, Isabel; Barros, M. Teresa; Maycock, Christopher D.


Book ID
120610926
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
615 KB
Volume
125
Category
Article
ISSN
0044-8249

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Copper-Catalyzed Synthesis of α-Amino Im
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α-Amino imides can be accessed straightforwardly from tertiary amines through copper-catalyzed three-component reactions involving the direct functionalization of sp(3) C-Hs adjacent to nitrogen atoms. This reaction has demonstrated a tolerance to a wide range of functionalizations and can be perfor