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Copper-Catalyzed Synthesis of α-Amino Imides from Tertiary Amines: Ugi-Type Three-Component Assemblies Involving Direct Functionalization of sp 3 C−Hs Adjacent to Nitrogen Atoms

✍ Scribed by Ye, Xin; Xie, Chunsong; Pan, Yuanyuan; Han, Laihong; Xie, Tian

Book ID
120595288
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
297 KB
Volume
12
Category
Article
ISSN
1523-7060

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Copper-Catalyzed Synthesis of α-Amino Im
Copper-Catalyzed Synthesis of α-Amino Imides from Tertiary Amines: Ugi-Type Three-Component Assemblies Involving Direct Functionalization of sp 3 C−Hs Adjacent to Nitrogen Atoms
✍ Ye, Xin; Xie, Chunsong; Pan, Yuanyuan; Han, Laihong; Xie, Tian 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 297 KB

α-Amino imides can be accessed straightforwardly from tertiary amines through copper-catalyzed three-component reactions involving the direct functionalization of sp(3) C-Hs adjacent to nitrogen atoms. This reaction has demonstrated a tolerance to a wide range of functionalizations and can be perfor