An efficient three-component coupling of aldehydes, amines and alkynes to prepare propargylamines, in nearly quantitative yields using nanocrystalline CuO as a catalyst is described. Structurally divergent aldehydes and amines were converted to the corresponding propargylamines. The reaction does no
✦ LIBER ✦
Copper-Catalyzed Diversity-Oriented Three- and Five- Component Synthesis of Mono- and Dipropargylic Amines via Coupling of Alkynes, α-Amino Esters and Aldehydes
✍ Scribed by Sharma, Nandini; Sharma, Upendra K.; Mishra, Nigam M.; Van der Eycken, Erik V.
- Book ID
- 124048339
- Publisher
- John Wiley and Sons
- Year
- 2014
- Tongue
- English
- Weight
- 512 KB
- Volume
- 356
- Category
- Article
- ISSN
- 1615-4150
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